{"id":32284,"date":"2024-03-03T19:35:05","date_gmt":"2024-03-03T19:35:05","guid":{"rendered":"https:\/\/kibrisdakik.com\/index.php\/2024\/03\/03\/insansilarin-kuyruklarini-nasil-kaybettigi-ortaya-cikti\/"},"modified":"2024-03-03T19:35:05","modified_gmt":"2024-03-03T19:35:05","slug":"insansilarin-kuyruklarini-nasil-kaybettigi-ortaya-cikti","status":"publish","type":"post","link":"https:\/\/kibrisdakik.com\/?p=32284","title":{"rendered":"\u0130nsans\u0131lar\u0131n kuyruklar\u0131n\u0131 nas\u0131l kaybetti\u011fi ortaya \u00e7\u0131kt\u0131"},"content":{"rendered":"

<\/p>\n

Bilim insanlar\u0131, insans\u0131lar\u0131n kuyruklar\u0131n\u0131n tek bir genetik de\u011fi\u015fiklik sonucunda 25 milyon y\u0131l \u00f6nce ortadan kalkm\u0131\u015f olabilece\u011fini belirledi.<\/p>\n

ABD’deki New York \u00dcniversitesi’nden (NYU) ara\u015ft\u0131rmac\u0131lar, \u00e7e\u015fitli kuyruklu maymun t\u00fcrlerinin DNA’lar\u0131n\u0131 insans\u0131lar\u0131nkiyle kar\u015f\u0131la\u015ft\u0131rd\u0131. <\/p>\n

\u0130ncelemelerde, insans\u0131larda mevcut olan fakat kuyruklu maymunlarda bulunmayan genetik varyantlara bak\u0131ld\u0131. 
\n <\/p>\n

Bilimsel dergi Nature’da \u00e7ar\u015famba g\u00fcn\u00fc yay\u0131mlanan ara\u015ft\u0131rmada, TBXT ad\u0131 verilen bir genin, bir\u00e7ok primatta kuyruk olu\u015fumundan sorumlu oldu\u011fu belirlendi. <\/p>\n

\u00c7al\u0131\u015fmada, Alu elementi ad\u0131 verilen bir transpozonun, bu genin i\u00e7ine yerle\u015fmesiyle kuyruk olu\u015fumu s\u00fcrecinin de\u011fi\u015fmeye ba\u015flad\u0131\u011f\u0131 ifade edildi.<\/p>\n

Transpozonlar, “s\u0131\u00e7rayan genler” olarak da bilinen ve transpozisyon diye adland\u0131r\u0131lan bir s\u00fcre\u00e7le h\u00fccrenin genomunda farkl\u0131 yerlere hareket edebilen DNA dizileri.  <\/p>\n

NYU’dan Itai Yanai, “Embriyonik geli\u015fim s\u0131ras\u0131nda kritik bir rol oynayan ve insans\u0131 olmayanlarda kuyruk geli\u015fimini d\u00fczenlemeyi sa\u011flayan TBXT geninde bir de\u011fi\u015fiklik tespit ettik” dedi. Bilim insan\u0131 s\u00f6zlerini \u015f\u00f6yle s\u00fcrd\u00fcrd\u00fc: <\/p>\n

\n

Bu mutasyon t\u00fcm insans\u0131larda g\u00f6r\u00fcl\u00fcyor. Dolay\u0131s\u0131yla bunun yakla\u015f\u0131k 25 milyon y\u0131l \u00f6nce insans\u0131 atalar\u0131n, g\u00fcn\u00fcm\u00fczdeki Eski D\u00fcnya maymunlar\u0131n\u0131n soyunu olu\u015fturan atalardan ayr\u0131ld\u0131\u011f\u0131 d\u00f6nemde ger\u00e7ekle\u015fti\u011fine dair iyi kan\u0131tlar\u0131m\u0131z var.<\/p>\n<\/blockquote>\n

Ara\u015ft\u0131rmac\u0131lar, fareler \u00fczerinde de deneyler yapt\u0131. \u0130nsans\u0131lardaki TBXT geni nakledilen farelerin, k\u0131sa kuyruklu ya da kuyruksuz do\u011fdu\u011fu g\u00f6zlemlendi. Ayr\u0131ca bu farelerde, bebeklerde g\u00f6r\u00fclen n\u00f6ral t\u00fcp defekti (NTD) olu\u015ftu\u011fu da aktar\u0131ld\u0131. <\/p>\n

Bebeklerde en s\u0131k g\u00f6r\u00fclen NTD, “ayr\u0131k omurga hastal\u0131\u011f\u0131” olarak da bilinen spina bifida’d\u0131r. Bu hastal\u0131kta omurgay\u0131 olu\u015fturan kemikler omurili\u011fi tamamen \u00f6rtmedi\u011finden, omurilik ve bununla ba\u011flant\u0131l\u0131 sinirler a\u00e7\u0131kta kal\u0131r. <\/p>\n

Yanai, fare deneyine de dikkat \u00e7ekerek “Bu, kuyru\u011fumuzu kaybetmeye y\u00f6nelik evrimsel bask\u0131n\u0131n o kadar b\u00fcy\u00fck oldu\u011funu g\u00f6steriyor ki, bu hastal\u0131klara yol a\u00e7ma ihtimaline ra\u011fmen yine de kuyru\u011fumuz ortadan kalkt\u0131” dedi.<\/p>\n

Ara\u015ft\u0131rmac\u0131, “Bu kadar b\u00fcy\u00fck bir anatomik d\u00f6n\u00fc\u015f\u00fcm\u00fcn, bu kadar k\u00fc\u00e7\u00fck bir genetik de\u011fi\u015fiklikten kaynaklanabilmesi \u015fa\u015f\u0131rt\u0131c\u0131” ifadelerini kulland\u0131.<\/p>\n","protected":false},"excerpt":{"rendered":"

Bilim insanlar\u0131, insans\u0131lar\u0131n kuyruklar\u0131n\u0131n tek bir genetik de\u011fi\u015fiklik sonucunda 25 milyon y\u0131l \u00f6nce ortadan kalkm\u0131\u015f olabilece\u011fini belirledi. ABD’deki New York \u00dcniversitesi’nden (NYU) ara\u015ft\u0131rmac\u0131lar, \u00e7e\u015fitli kuyruklu maymun t\u00fcrlerinin DNA’lar\u0131n\u0131 insans\u0131lar\u0131nkiyle kar\u015f\u0131la\u015ft\u0131rd\u0131.  \u0130ncelemelerde, insans\u0131larda mevcut olan fakat kuyruklu maymunlarda bulunmayan genetik varyantlara bak\u0131ld\u0131.    Bilimsel dergi Nature’da \u00e7ar\u015famba g\u00fcn\u00fc yay\u0131mlanan ara\u015ft\u0131rmada, TBXT ad\u0131 verilen bir genin, bir\u00e7ok primatta kuyruk<\/p>\n","protected":false},"author":1,"featured_media":32285,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[85],"tags":[],"class_list":["post-32284","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-spor"],"yoast_head":"\n\u0130nsans\u0131lar\u0131n kuyruklar\u0131n\u0131 nas\u0131l kaybetti\u011fi ortaya \u00e7\u0131kt\u0131 -<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/kibrisdakik.com\/?p=32284\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u0130nsans\u0131lar\u0131n kuyruklar\u0131n\u0131 nas\u0131l kaybetti\u011fi ortaya \u00e7\u0131kt\u0131 -\" \/>\n<meta property=\"og:description\" content=\"Bilim insanlar\u0131, insans\u0131lar\u0131n kuyruklar\u0131n\u0131n tek bir genetik de\u011fi\u015fiklik sonucunda 25 milyon y\u0131l \u00f6nce ortadan kalkm\u0131\u015f olabilece\u011fini belirledi. 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