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<\/div>\n2024 Nobel T\u0131p \u00d6d\u00fcl\u00fc, \u201cmikroRNA\u2019n\u0131n ke\u015ffi ve transkripsiyon sonras\u0131 gen d\u00fczenlemesindeki rol\u00fc\u201d \u00e7al\u0131\u015fmalar\u0131na imza atan ABD as\u0131ll\u0131 Victor Ambros ve Gary Ruvkun\u2019a verildi.<\/p>\n
\u0130sve\u00e7\u2019te bulunan Karolinska Enstit\u00fcs\u00fcnde d\u00fczenlenen bas\u0131n toplant\u0131s\u0131nda, 2024 Nobel T\u0131p \u00d6d\u00fcl\u00fc sahipleri a\u00e7\u0131kland\u0131.<\/p>\n
Ambros ve Ruvkun, \u201cmikroRNA\u2019n\u0131n ke\u015ffi ve transkripsiyon sonras\u0131 gen d\u00fczenlemesindeki rol\u00fc\u201d alan\u0131ndaki \u00e7al\u0131\u015fmalar\u0131ndan dolay\u0131 \u00f6d\u00fcle lay\u0131k g\u00f6r\u00fcld\u00fc.<\/p>\n
\u0130kili, gen d\u00fczenlemesinde \u00f6nemli rol oynayan yeni bir k\u00fc\u00e7\u00fck RNA molek\u00fcl\u00fc mikroRNA\u2019y\u0131 ke\u015ffetti ve bulgular\u0131 yeni bir gen d\u00fczenleme prensibini ortaya \u00e7\u0131kard\u0131.<\/p>\n
S\u00f6z konusu \u00e7al\u0131\u015fma mikroRNA\u2019lar\u0131n insanlar dahil \u00e7ok h\u00fccreli organizmalar i\u00e7in gerekli oldu\u011funu, organizmalar\u0131n geli\u015fip \u00e7al\u0131\u015fmas\u0131 i\u00e7in de \u00f6nemli bir role sahip oldu\u011funu g\u00f6sterdi.<\/p>\n
\u2013 Ambros ve Ruvkun kimdir?<\/strong><\/p>\n Victor R. Ambros, ABD\u2019nin, New Hampshire eyaletinde 1953\u2019te d\u00fcnyaya geldi. Lisans derecesini 1975 y\u0131l\u0131nda Massachusetts Teknoloji Enstit\u00fcs\u00fcnde (MIT) biyoloji alan\u0131nda tamamlayan Ambros, doktoras\u0131n\u0131 1979 y\u0131l\u0131nda ayn\u0131 \u00fcniversiteden ald\u0131.<\/p>\n Ambros, 2008\u2019den bu yana Massachusetts \u00dcniversitesi T\u0131p Fak\u00fcltesi\u2019nde \u00e7al\u0131\u015f\u0131yor.<\/p>\n ABD\u2019nin California eyaletinde 1952\u2019de do\u011fan Gary Ruvkun, lisans e\u011fitimini 1973\u2019de Berkeley\u2019deki California \u00dcniversitesi\u2019nde tamamlad\u0131. Ruvkun, doktoras\u0131n\u0131 \u201cbakteriyel azot fiksasyon genleri\u201d \u00e7al\u0131\u015fmalar\u0131yla Harvard \u00dcniversitesi\u2019nden ald\u0131.<\/p>\n Ruvkun, Harvard T\u0131p Fak\u00fcltesi\u2019nde genetik profes\u00f6r\u00fc olarak g\u00f6rev yap\u0131yor.<\/p>\n 2023 Nobel T\u0131p \u00d6d\u00fcl\u00fc, mRNA i\u00e7erikli Kovid-19 a\u015f\u0131s\u0131n\u0131n geli\u015ftirilmesini sa\u011flayan \u00e7al\u0131\u015fmalara imza atan 68 ya\u015f\u0131ndaki Macar as\u0131ll\u0131 bilim insan\u0131 Katalin Kariko ve 64 ya\u015f\u0131ndaki ABD\u2019li bilim insan\u0131 Drew Weissman\u2019a verilmi\u015fti.<\/p>\n \u2013 Nobel \u00d6d\u00fclleri hakk\u0131nda<\/strong><\/p>\n \u0130sve\u00e7li Alfred Nobel\u2019in vasiyeti \u00fczerine \u00f6l\u00fcm\u00fcnden sonra 9 Haziran 1900\u2019de kurulan Nobel Vakf\u0131n\u0131n insanl\u0131\u011fa hizmette bulunanlara verdi\u011fi \u00f6d\u00fcller, d\u00fcnyada en sayg\u0131n \u00f6d\u00fcller olarak kabul ediliyor.<\/p>\n Nobel \u00d6d\u00fclleri, \u0130sve\u00e7 Kraliyet Bilimler Akademisi, \u0130sve\u00e7 Akademisi, Karolinska Enstit\u00fcs\u00fc ve Norve\u00e7 Nobel Komitesi taraf\u0131ndan, fizik, kimya, edebiyat, bar\u0131\u015f ve t\u0131p olmak \u00fczere 5 dalda en ba\u015far\u0131l\u0131 kabul edilen ki\u015filer veya kurulu\u015flara veriliyor.<\/p>\n Bunlara ek olarak, Nobel Ekonomi \u00d6d\u00fcl\u00fc, 1968\u2019de \u0130sve\u00e7 Merkez Bankas\u0131n\u0131n Alfred Nobel\u2019in an\u0131s\u0131na ekonomi dal\u0131nda da \u00f6d\u00fcl verilmesini kararla\u015ft\u0131rmas\u0131yla, ilk kez 1969\u2019da verildi.<\/p>\n Nobel \u00d6d\u00fclleri, her y\u0131l Alfred Nobel\u2019in \u00f6l\u00fcm y\u0131l d\u00f6n\u00fcm\u00fc olan 10 Aral\u0131k\u2019ta d\u00fczenlenen t\u00f6renle sahiplerine teslim ediliyor.<\/p>\n \u00d6te yandan \u00f6d\u00fcllerin 1901\u2019deki ba\u015flang\u0131c\u0131ndan bu yana verilmedi\u011fi birka\u00e7 y\u0131l oldu. Toplamda 49 defa yap\u0131lan \u00f6d\u00fcl iptallerinin \u00e7o\u011fu Birinci ve \u0130kinci D\u00fcnya Sava\u015flar\u0131 s\u0131ras\u0131nda ger\u00e7ekle\u015fti.<\/p>\n \u00d6d\u00fcl t\u00f6renleri, Kovid-19 salg\u0131n\u0131 nedeniyle 2020 ve 2021\u2019de de yap\u0131lamam\u0131\u015ft\u0131.<\/p>\n<\/p><\/div>\n