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<\/div>\nYap\u0131lan ara\u015ft\u0131rmalara g\u00f6re, A kan grubuna sahip ki\u015filer, di\u011fer kan gruplar\u0131na k\u0131yasla 60 ya\u015f\u0131ndan \u00f6nce fel\u00e7 ge\u00e7irme olas\u0131l\u0131\u011f\u0131 daha y\u00fcksek bir riskle kar\u015f\u0131 kar\u015f\u0131ya.<\/p>\n
Kan gruplar\u0131, k\u0131rm\u0131z\u0131 kan h\u00fccrelerinin y\u00fczeyinde bulunan kimyasal \u00e7e\u015fitlili\u011fi tan\u0131mlar.<\/p>\n
A ve B olarak bilinen bu gruplar, AB olarak birlikte, A ya da B olarak tek ba\u015f\u0131na ya da hi\u00e7 bulunmayarak O grubu \u015feklinde s\u0131n\u0131fland\u0131r\u0131lmaktad\u0131r.<\/p>\n
2022 y\u0131l\u0131nda yap\u0131lan bir \u00e7al\u0131\u015fmada, genom ara\u015ft\u0131rmac\u0131lar\u0131 A1 alt grubuna ait gen ile erken ya\u015fta fel\u00e7 ge\u00e7irme riski aras\u0131nda net bir ili\u015fki ke\u015ffetti.<\/p>\n
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<\/div>\nBu \u00e7al\u0131\u015fma, yakla\u015f\u0131k 17 bin fel\u00e7 vaka<\/a>s\u0131 ve 600 bine yak\u0131n fel\u00e7 ge\u00e7irmemi\u015f ki\u015fiyi kapsayan 48 genetik \u00e7al\u0131\u015fman\u0131n verilerini analiz etti.<\/p>\n \u00c7al\u0131\u015fmadaki kat\u0131l\u0131mc\u0131lar\u0131n ya\u015f aral\u0131\u011f\u0131 ise 18 ile 59 aras\u0131ndayd\u0131.<\/p>\n O grubu gen varyasyonuna sahip ki\u015filerde risk y\u00fczde 12 daha d\u00fc\u015f\u00fck<\/strong> Ara\u015ft\u0131rman\u0131n ba\u015f yazar\u0131 ve vask\u00fcler n\u00f6rolog Steven Kittner, \u201cA kan grubunun neden daha y\u00fcksek bir risk sundu\u011funu hen\u00fcz bilmiyoruz\u201d diyerek, bu durumun kan p\u0131ht\u0131la\u015fma fakt\u00f6rleri, kan damarlar\u0131n\u0131 kaplayan h\u00fccreler ve dola\u015f\u0131mdaki proteinlerle ilgili olabilece\u011fini belirtti.<\/p>\n Her y\u0131l ABD\u2019de yakla\u015f\u0131k 800 bin ki\u015fi fel\u00e7 ge\u00e7iriyor ve bu vaka<\/a>lar\u0131n \u00e7o\u011fu 65 ya\u015f \u00fcst\u00fcnde g\u00f6r\u00fcl\u00fcyor. Fel\u00e7 riski, 55 ya\u015f\u0131ndan sonra her on y\u0131lda bir iki kat\u0131na \u00e7\u0131k\u0131yor.<\/p>\n \u00c7al\u0131\u015fman\u0131n bulgular\u0131, \u00f6zellikle gen\u00e7 ya\u015fta g\u00f6r\u00fclen fel\u00e7lerin, ileri ya\u015fta meydana gelen fel\u00e7lerden farkl\u0131 mekanizmalarla ortaya \u00e7\u0131kabilece\u011fini de ortaya koyuyor.<\/p>\n Gen\u00e7 bireylerdeki fel\u00e7 vaka<\/a>lar\u0131n\u0131n, arterlerde ya\u011f birikiminden ziyade p\u0131ht\u0131 olu\u015fumu ile ilgili oldu\u011fu d\u00fc\u015f\u00fcn\u00fcl\u00fcyor.<\/p>\n Bu \u00e7al\u0131\u015fma, A kan grubuna sahip ki\u015filerin, \u00f6zellikle gen\u00e7 ya\u015flarda, fel\u00e7 riskini g\u00f6z ard\u0131 etmemesi gerekti\u011fini bir kez daha g\u00f6steriyor.<\/p>\n<\/p><\/div>\n
\u00c7al\u0131\u015fman\u0131n sonu\u00e7lar\u0131na g\u00f6re, A grubuna ait genetik varyasyonu ta\u015f\u0131yan ki\u015filerin 60 ya\u015f\u0131ndan \u00f6nce fel\u00e7 ge\u00e7irme riski, di\u011fer kan gruplar\u0131na sahip ki\u015filere k\u0131yasla y\u00fczde 16 daha y\u00fcksek. \u00d6te yandan, O grubu gen varyasyonuna sahip ki\u015filerde ise bu risk y\u00fczde 12 daha d\u00fc\u015f\u00fck.<\/p>\n