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<\/div>\nKalbin yaln\u0131zca beyin taraf\u0131ndan kontrol edildi\u011fi d\u00fc\u015f\u00fcncesi, bilim insanlar\u0131n\u0131n yapt\u0131\u011f\u0131 \u00e7arp\u0131c\u0131 bir ke\u015fifle de\u011fi\u015fiyor. \u0130sve\u00e7\u2019teki Karolinska Enstit\u00fcs\u00fc ve ABD\u2019deki Columbia \u00dcniversitesi\u2019nden ara\u015ft\u0131rmac\u0131lar, kalbin kendi sinir sistemine sahip oldu\u011funu ortaya \u00e7\u0131kard\u0131. \u201cMini beyin\u201d olarak adland\u0131r\u0131la ba\u011f\u0131ms\u0131z sinir sistemi, kalbin ritmini d\u00fczenliyor.<\/p>\n
Uzun y\u0131llard\u0131r kalbin, beyinle ba\u011flant\u0131l\u0131 otonom sinir sistemi arac\u0131l\u0131\u011f\u0131yla kontrol edildi\u011fi d\u00fc\u015f\u00fcn\u00fcl\u00fcyordu.<\/p>\n
Ancak ara\u015ft\u0131rma, kalp duvar\u0131nda yer alan bu sinir a\u011f\u0131n\u0131n d\u00fc\u015f\u00fcn\u00fcld\u00fc\u011f\u00fcnden \u00e7ok daha karma\u015f\u0131k bir yap\u0131ya sahip oldu\u011funu ve ritim d\u00fczenlemesinde ba\u011f\u0131ms\u0131z bir rol \u00fcstlendi\u011fini g\u00f6sterdi.<\/p>\n
Karolinska Enstit\u00fcs\u00fc\u2019nden Do\u00e7. Dr. Konstantinos Ampatzis, \u201cBu k\u00fc\u00e7\u00fck beyin, t\u0131pk\u0131 beynin solunum veya hareket gibi ritmik fonksiyonlar\u0131 d\u00fczenledi\u011fi gibi, kalp at\u0131\u015f\u0131n\u0131 kontrol etmede hayati bir rol oynuyor\u201d a\u00e7\u0131klamas\u0131nda bulundu.<\/p>\n
Ara\u015ft\u0131rmada, kalpte farkl\u0131 i\u015flevlere sahip birden fazla n\u00f6ron t\u00fcr\u00fc tespit edildi. Bunlardan biri, kalbin \u201cdo\u011fal uyar\u0131c\u0131\u201d g\u00f6revini \u00fcstlenen bir grup n\u00f6ron. Bu ke\u015fif, kalp ritminin nas\u0131l kontrol edildi\u011fine dair mevcut g\u00f6r\u00fc\u015fleri de\u011fi\u015ftirirken, klinik a\u00e7\u0131dan da yeni ufuklar a\u00e7\u0131yor.<\/p>\n
Yeni tedavi y\u00f6ntemleri i\u00e7in umut<\/strong> Dr. Ampatzis, \u201cKalbin sinir a\u011f\u0131 ile beyin aras\u0131ndaki etkile\u015fimi, egzersiz, stres veya hastal\u0131k gibi farkl\u0131 ko\u015fullarda ara\u015ft\u0131rmaya devam edece\u011fiz. Kalbin n\u00f6ral a\u011f\u0131ndaki bozulmalar\u0131n \u00e7e\u015fitli kalp rahats\u0131zl\u0131klar\u0131na nas\u0131l katk\u0131 sa\u011flad\u0131\u011f\u0131n\u0131 inceleyerek yeni tedavi hedefleri belirlemeyi ama\u00e7l\u0131yoruz\u201d dedi.<\/p>\n<\/p><\/div>\n
\u00c7al\u0131\u015fma, insan kalbiyle benzer ritim ve i\u015flevlere sahip zebra bal\u0131klar\u0131 \u00fczerinde ger\u00e7ekle\u015ftirildi. Ara\u015ft\u0131rmac\u0131lar, tek h\u00fccre RNA dizilemesi, anatomik incelemeler ve elektrofizyolojik y\u00f6ntemler kullanarak kalpteki n\u00f6ronlar\u0131n yap\u0131s\u0131n\u0131, organizasyonunu ve i\u015flevini haritaland\u0131rd\u0131.<\/p>\n