\n
\n\tFaz 3 klinik \u00e7al\u0131\u015fmaya g\u00f6re Verzenio, lenf d\u00fc\u011f\u00fcmlerine yay\u0131lm\u0131\u015f y\u00fcksek riskli erken evre meme kanseri hastalar\u0131nda n\u00fcks riskini belirgin \u015fekilde azaltt\u0131.<\/p>\n
\n\t5 bin 637 hasta \u00fczerinde y\u00fcr\u00fct\u00fclen denemede, yaln\u0131zca hormon tedavisi alanlara k\u0131yasla Verzenio ile kombine tedavi g\u00f6renlerde sa\u011fkal\u0131m oran\u0131 anlaml\u0131 \u00f6l\u00e7\u00fcde artt\u0131.<\/p>\n
\n\tHen\u00fcz hakemli dergilerde yay\u0131mlanmayan sonu\u00e7lar, \u00f6n\u00fcm\u00fczdeki d\u00f6nemde bilimsel kongrelerde payla\u015f\u0131lacak.<\/p>\n
\n\tFDA onay\u0131 ve geni\u015fleyen kullan\u0131m<\/h2>\n
\n\tVerzenio, ABD G\u0131da ve \u0130la\u00e7 Dairesi (FDA) taraf\u0131ndan ilk kez 2017\u2019de ileri evre veya metastatik meme kanseri i\u00e7in onayland\u0131. Hormon resept\u00f6r\u00fc pozitif (HR+), HER2-negatif hastalarda kullan\u0131lan ila\u00e7, 2023\u2019te erken evre y\u00fcksek riskli vakalara da onay ald\u0131.<\/p>\n
\n\tBu tip kanser, t\u00fcm meme kanseri vakalar\u0131n\u0131n yakla\u015f\u0131k y\u00fczde 70\u201380\u2019ini olu\u015fturuyor. HR+ t\u00fcm\u00f6rler, \u00f6strojen ve progesteron gibi hormonlarla etkile\u015ferek b\u00fcy\u00fcyor. Verzenio ise h\u00fccre b\u00f6l\u00fcnmesinden sorumlu enzimleri bask\u0131layarak t\u00fcm\u00f6r \u00e7o\u011falmas\u0131n\u0131 durduruyor.<\/p>\n
\n\tUzmanlardan de\u011ferlendirme<\/h2>\n
\n\tLilly Oncology Ba\u015fkan\u0131 Jacob Van Naarden, \u201cBu veriler, Verzenio\u2019nun y\u00fcksek riskli HR+, HER2-negatif erken evre meme kanserinde standart tedavi olarak \u00f6nemini do\u011fruluyor. Hastalar\u0131n hastal\u0131\u011f\u0131n tekrarlamas\u0131n\u0131 engellemek ve ya\u015fam s\u00fcresini uzatmak en y\u00fcksek hedefimiz.\u201d ifadelerini kulland\u0131.<\/p>\n
\n\tSadece ge\u00e7en y\u0131l 5,3 milyar dolar sat\u0131\u015f yapan ila\u00e7, Lilly\u2019nin en \u00f6nemli kanser tedavilerinden biri haline geldi.<\/p>\n
\n\tMeme kanserinde farkl\u0131 alt tipler<\/h2>\n
\n\tHR+, HER2-negatif: En s\u0131k g\u00f6r\u00fclen ve tedaviye en iyi yan\u0131t veren tip.<\/p>\n
\n\t\u00dc\u00e7l\u00fc negatif (Triple-negative): En agresif t\u00fcr; hormon ve HER2 resept\u00f6rleri bulunmad\u0131\u011f\u0131 i\u00e7in tedavisi zor.<\/p>\n
\n\tYeni veriler, HR+ ve HER2-negatif hastalarda n\u00fcks\u00fc \u00f6nlemede iki y\u0131ll\u0131k Verzenio + hormon tedavisinin g\u00fc\u00e7l\u00fc bir fark yaratt\u0131\u011f\u0131n\u0131 ortaya koyuyor.<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"
Faz 3 klinik \u00e7al\u0131\u015fmaya g\u00f6re Verzenio, lenf d\u00fc\u011f\u00fcmlerine yay\u0131lm\u0131\u015f y\u00fcksek riskli erken evre meme kanseri hastalar\u0131nda n\u00fcks riskini belirgin \u015fekilde azaltt\u0131.
5 bin 637 hasta \u00fczerinde y\u00fcr\u00fct\u00fclen denemede, yaln\u0131zca hormon tedavisi alanlara k\u0131yasla Verzenio ile kombine tedavi g\u00f6renlerde sa\u011fkal\u0131m oran\u0131 anlaml\u0131 \u00f6l\u00e7\u00fcde artt\u0131.
Hen\u00fcz hakemli dergilerde yay\u0131mlanmayan sonu\u00e7lar, \u00f6n\u00fcm\u00fczdeki d\u00f6nemde bilimsel kongrelerde<\/p>\n","protected":false},"author":1,"featured_media":91483,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[101,86],"tags":[],"class_list":["post-91482","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-manset","category-turkiye"],"yoast_head":"\n
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Faz 3 klinik \u00e7al\u0131\u015fmaya g\u00f6re Verzenio, lenf d\u00fc\u011f\u00fcmlerine yay\u0131lm\u0131\u015f y\u00fcksek riskli erken evre meme kanseri hastalar\u0131nda n\u00fcks riskini belirgin \u015fekilde azaltt\u0131.
5 bin 637 hasta \u00fczerinde y\u00fcr\u00fct\u00fclen denemede, yaln\u0131zca hormon tedavisi alanlara k\u0131yasla Verzenio ile kombine tedavi g\u00f6renlerde sa\u011fkal\u0131m oran\u0131 anlaml\u0131 \u00f6l\u00e7\u00fcde artt\u0131.
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